At Recursion, we combine experimental biology, automation, and artificial intelligence to quickly and efficiently identify treatments for human diseases. Our approach to scalable, high-dimensional biology allows us to discover potential treatments for many diseases at a rapid pace. Our Disease Biology team identifies advanced and biologically-relevant in vitro models, across a number of therapeutic areas, and then uses advanced high-dimensional assays to push the boundaries of our platform.

 

THE PROBLEMS YOU’LL SOLVE

Our Disease Biology team is a scientifically-curious and driven group that performs disease validation assays in support of prioritization of compound hits for further research and development. As a Research Associate, you will be responsible for the execution, analysis, and reporting on multiple concurrent experiments. This will involve the use of traditional wet-bench techniques, tissue culture, microscopy, and various liquid handling machinery to help develop novel assays.

This role is ideal if you are someone who enjoys introducing a different perspective, values process improvement, questions conventional thought, believes that the devil is in the details, and has what we like to call “golden hands.”

For this role, we are looking for researchers who are:

  • Detail-oriented - We want researchers who sweat the small stuff. Precision, accuracy, and perseverance are crucial to this position and will be rewarded.
  • Results-driven - Patients are waiting for the drug therapies that we are discovering, so we need researchers who generate high quality data to drive decisions in a timely manner.
  • Imaginative  - We need researchers who get a thrill out of solving problems. Some of these problems we may not realize we have yet. You will help us identify opportunities for success and design experiments to test our (and your) hypotheses.
  • Hands on - The lab is your domain and you will be using your traditional wet-lab skills to design and execute new processes on our state-of-the-art equipment.

 

WHAT YOU’LL NEED

  • Bachelor’s of Science, Master’s of Science or equivalent in cellular and molecular biology, biochemistry, physiology, pharmacology or related field
  • 2-3 years of experience in tissue culture and basic molecular lab techniques are a must.  Experience with automation, assay development, assay validation, and experimental design strongly desired. We count Master’s thesis research work and hands-on lab research as applicable experience
  • An ability to work independently and as part of a multidisciplinary team
  • Proven interpersonal communication and writing skills (experimental reporting)

THE PERKS YOU’LL ENJOY

  • Coverage of health, vision, and dental insurance premiums (in most cases 100%)
  • 401(k) with generous matching (immediate vesting)
  • Stock option grants
  • Two one-week paid company closures (summer and winter) in addition to flexible, generous vacation/sick leave
  • Commuter benefit and vehicle parking to ease your commute
  • Complimentary chef-prepared lunches and well-stocked snack bars
  • Generous paid parental leave (including adoptive)
  • Fully-paid gym membership to Metro Fitness, located just feet away from our new headquarters
  • Gleaming new 100,000 square foot headquarters complete with a 70-foot climbing wall, showers, lockers, and bike parking

WHAT WE DO

We start with various human cell types in our automated laboratory, where we perturb biology 100k different ways each week (e.g. model a disease of interest, add a chemical compound, or some combination of those). We image the resulting cells using high throughput microscopy, resulting in about 2 million new images or greater than 20 terabytes of data each week. These data are analyzed using computer vision and machine learning methods that help us measure how cell morphology changes in subtle ways in each biological context. We can answer direct questions (e.g. are there compounds that rescues a disease-specific set of morphological changes), and over time as our dataset has increased, we can ask more complex questions across biology. From the outset, our approach is agnostic to preconceived notions and dogma in biology, enabling Recursion to operate in novel target space. Potential  treatments from this platform are then evaluated by our discovery biology team, who develop a literature-based understanding of the disease and use traditional wet-lab approaches to confirm and prioritize the hits.

Recursion is an equal opportunity employer and complies with all applicable federal, state, and local fair employment practices laws. Recursion strictly prohibits and does not tolerate discrimination against applicants because of race, color, religion, creed, national origin or ancestry, ethnicity, sex, pregnancy, gender (including gender nonconformity and status as a transgender individual), age, physical or mental disability, citizenship, past, current, or prospective service in the uniformed services, or any other characteristic protected under applicable federal, state, or local law.

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